Source (restricted to non-HBO-Max regions)
Kamala Harris is known to love Venn diagrams and would be cringing hard at this.
For reference, circles in Venn (Euler) diagrams are sets of objects with a certain property. Select objects are shown inside or outside of each circle depending on whether they belong to the set.
A good example is xkcd 2962:
He has a live audience so he (and the writing team) knows what’s funny, and limits self-deprecation to about twice per episode. The show mostly features more conventional joke material (references to pop culture, defying expectations, reframing events in surprising context).
Its even funnier when you explain it.
It’s ok if the humour isn’t for you
You are correct. Self-deprecation is overdone in this corner of the internet so we’ve grown numb to it, while a live or TV audience largely hasn’t, as evidenced by the laughter. As I said, they use many other kinds of humor too, which might appeal to you. JO is known for slandering his show, haircuts, nationality etc. but not too often.
It sounds more like humor in general is not for them 😅