Hi everyone! I was diagnosed a few years ago in my early 30s, and started taking Adderall along with some different drugs for anxiety as well.

With Adderall and then Wellbutrin, even in small dosages, I notice that my HRV Stress (recorded on a Garmin 945 Forerunner) is significantly elevated for the entire day. When I used to take a midday and evening dose of (instant release) Adderall, it severely impacted my sleep. I also tried extended release taken in the morning, and that caused sleeping issues as well. So did an extended release of Wellbutrin.

Basically, any benefits those medications provide (and it didn’t really feel like it was helping) were offset by the bodily impact.

Has anyone had a similar experience with either of these medications? Any notable co-morbidities or changed metabolism or something that you identified as causing these symptoms? Did Ritalin or Strattera work for you when Adderall did not? I’ve been cycling through other non-stim medications with my provider, but haven’t found anything that provides benefits for ADHD (I’m currently on guanfacine and zoloft, which mitigates my anxiety at least).

  • @jubilationtcornpone
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    119 days ago

    SSRI’s can cause issues with stimulant medications primarily for two reasons. They increase the effectiveness of the stimulant and they increase the level of serotonin in your blood. Too much serotonin is not good. Look up “seratonin syndrome” and see if you’re experiencing any other symptoms.

    Those meds can be taken together but there probably needs to be a dosage adjustment to one or both of them.

    Also, if you’re not already, avoid caffeine completely.

    • @[email protected]OP
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      119 days ago

      I haven’t taken sertraline and Adderall at the same time. But this is good information to know, I’ll look up the symptoms. Thanks!