Nnnno. Biological sex predates mammalia. There’s some fuzz at the boundaries, because biology is squidgy and gross, but the overwhelming majority of humans are not ambiguously sexed in any way. Most people are either born with XX chromosomes and a normal-ish vagina, or XY chromosomes and a normal-ish penis.

The video author is thinking of gender. Gender is the made-up part where any societal distinction is placed on this anatomy. But barring significant elective surgery, the author almost certainly has a biological sex that could be immediately and rudely verified. That does affect every person’s existence, even if they’re trans, because (for example) not many women get prostate cancer. If you’ve got one then you have to worry about it.

Sex is not “an appeal to the gender binary.” That’s completely backwards. Gender is an appeal to sex, often in the same way racial stereotypes are an appeal to skin color. There are associated differences… but they’re never what assholes are shouting about.