Although the budget would continue support for ongoing missions such as the Hubble Space Telescope and the James Webb Space Telescope, it would kill the much-anticipated Nancy Grace Roman Space Telescope, an observatory seen as on par with those two world-class instruments that is already fully assembled and on budget for a launch in two years.

Other significant cuts include ending funding for Mars Sample Return as well as the DAVINCI mission to Venus. The budget cuts also appear intended to force the closure of Goddard Space Flight Center in Maryland where the agency has 10,000 civil servants and contractors.