Cutscenes can be memorable for many reasons, such as their emotional impact, their humor, their shock value, or their artistic quality. Some cutscenes are so iconic that they have become part of gaming culture and history.
Which one is burned into your memory?
It’s from Mass Effect, this is the character Mordin Solus catchphrase. CosmicApe is almost certainly refering to a (very good) cutsceen from one of the possible endings to the Tuchanka chain of missions in ME3.
Is this from the scene where Mordin is up in the tower?
That’s the one