Several elected leaders in Oregon declared a state of emergency on Tuesday for downtown Portland over the public health and public safety crisis fueled by fentanyl.

Oregon Gov. Tina Kotek, Portland Mayor Ted Wheeler and Multnomah County Chair Jessica Vega Pederson made the declaration for a 90-day period during which collaboration and response will come from a command center downtown. The three governments are directing their agencies to work with first responders in connecting people addicted to the synthetic opioid with resources including drug treatment programs and to crack down on drug sales.

“Our country and our state have never seen a drug this deadly addictive, and all are grappling with how to respond,” Kotek said in a statement.