For me:
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Breath of the Wild: 400 hours in, have done only 50% of the game. But now that TotK is out, I’m not sure if I’ll ever complete BotW. Perhaps if I’m stuck on a deserted island with my Switch and have nothing better to do, I may pick it up again.
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Skyrim: Countless hours, never really done much of the main storyline, always get lost in modding and optimising the game. Own it on practically all platforms too. But one of these days, I’ll get to the main quest…
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Dangerous Dave: Been playing this DOS game on and off since 1990 but still haven’t managed to beat it. I always die around level 6/7, blasted sun keeps killing me.
Probably Europa Universalis 4. I’ve played dozens of campaigns, and clocked in hundreds of hours (>850), and I have yet to make it more than 2/3 of the way through the campaign time. I usually have a specific win condition I’m interested in (e.g. an achievement, or cool scenario), and once I hit it, I don’t bother continuing the campaign.
Other than that, I tend to bail on most RPGs around 50 hours in, so I’ve never finished any Elder Scrolls, Final Fantasy, etc despite starting numerous times. I feel like I bail when I get too powerful, need to grind because I’m not powerful enough, the story drags and I lose track of the main story line. I still keep starting them, but I almost never finish them.