If we do the same thing for millions of years, I don’t think other organisms would develop defenses (against what?), but rather they’d adapt to living embedded in our civilization, as a new biome. Kind of what commensals (pigeons, rats) and domesticates (cows, cats) are doing, but much further. There would be complex relationships between them, which would make our civilization a mature ecosystem.
If we do the same thing for millions of years, I don’t think other organisms would develop defenses (against what?), but rather they’d adapt to living embedded in our civilization, as a new biome. Kind of what commensals (pigeons, rats) and domesticates (cows, cats) are doing, but much further. There would be complex relationships between them, which would make our civilization a mature ecosystem.