No direct flights in most cases, only hopping through third countries, partially because since the war started and there was a problem in money transfer, import and foreign expertise, they ‘nationalized’ the planes their companies leased\bought (?) and service them with whatever parts availiable to them at the schedule they themselves choose.
IIRC Finland closed the direct entry by land from St. Petersburg. Don’t know about others.
Personal sanctions and Internation Court’s decisions are also there but they don’t touch relatives or associates.
From the top of my head:
Mostly, it became more expensive.