I don’t know whether they even had any data on change difficulty. I think it was more like - we needed a vaccine yesterday and Moderna and BioNTech had the mRNA technology just ready to be able to spin up a vaccine quickly. And that was good enough to save a lot of people from severe disease.
They definitely had something, I remember reading about it at the time. it might have involved what they knew about previous coronavirus’s as well. Whatever they had though it ended up being wrong.
The vaccines initially did just that, it just turns out it was able to adapt anyway or they were wrong.
I don’t know whether they even had any data on change difficulty. I think it was more like - we needed a vaccine yesterday and Moderna and BioNTech had the mRNA technology just ready to be able to spin up a vaccine quickly. And that was good enough to save a lot of people from severe disease.
They definitely had something, I remember reading about it at the time. it might have involved what they knew about previous coronavirus’s as well. Whatever they had though it ended up being wrong.