Non-Terrestrial Networks (NTNs) and satellite systems have become an important component of modern data communication systems in recent years. Despite their importance, the security of these systems is often limited, leaving them vulnerable to determined attackers. In this paper, we outline a scenario in which an attacker can infect an in-orbit NASA Core Flight System (cFS) based satellite with ransomware and communicate the infection back to a satellite operator. This paper is the first to demonstrate an end-to-end exploit path that results in a ransomware infection without the need for a supply chain attack or compromised credentials. Novel ransomware is delivered to an emulated satellite system using custom shellcode that exploits a weakness in the considered scenario. The scenario considered by this initial piece of work achieves a success rate of 33.3\% for a complete successful infection.