Children and adolescents were at higher risk for new-onset mild and moderate chronic kidney disease from 2020 to 2023.

COVID-19 infection was linked to a higher risk of new-onset mild and moderate chronic kidney disease (CKD) in US children and adolescents from 2020 to 2023, according to recent findings from the National Institutes of Health’s Researching COVID to Enhance Recovery (RECOVER) initiative.

The University of Pennsylvania-led research team assessed data on kidney outcomes from 1.9 million patients aged 20 years and younger with (487,400) and without (1.4 million) COVID-19 at 19 healthcare centers from March 2020 to May 2023, with up to 2 years of follow-up. The average age was 8.2 years, 51.0% were male, and 45% were White.

The results were published late last week in JAMA Network Open.