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The original was posted on /r/todayilearned by /u/WitchThatShit on 2023-07-02 06:53:01+00:00.
Original Title: TIL Redheads tend to need more anesthesia than those with darker hair, because of their MC1R gene. This gene not only influences a person’s pigmentation, but it’s been speculated to also influence their pain perception.
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Yup can confirm, the amount of times I’ve had to have a “top up” during a dentist appointment. I’ve finally found a dentist now that will give me 3 shots before he even starts. Also morphine and methadone does piss all, Tramadol wheres is at!