I’d just pickup another set of ram that matches for speed/timings (I’d run 64GB of 3200mhz myself) and double or triple your ram capacity. that will give you a nice uplift without any other bs, maybe do a nice once over of your system (evict the dust bunnies) a BIOS update, (you will likely find some nice smaller QOL updates vs early bios)

If you the full core system refresh route…
your going to have 5 Generations of IPC uplift in one hit which will likely feel sprightly on top of the extra cores and iGPU upgrade. (again, for Ram compatibility and QOL updates do a bios update on the new combo early on) prep a USB with the bios and have another with all the key drivers you will need to install for intel drivers, igpu, nvidia drivers and anything else you want early on like Ninite for instance.

DDR5 is starting to be come more widely available at decent prices, so if you can swing a 64GB kit now, do it and grab another down the line as it gets cheaper. IF DDR5 on a BOARD and RAM cost is killing your hip pocket remember you can still get the DDR4 Equivalent you still get all the I/O improvements and IPC gain, and a decent lift to DDR4 performance but not as much as youd get with DDR5 (think 11-15% under)

I’d also suggest grabbing a A770 LE while you can if you do video/streaming or editing work, the newer drivers are making that card a great performer.