Tested in my OptiPlex 7060 with i5 8500. Worked fine. Just had to install the Wi-Fi and Bluetooth drivers from the Intel website as they’re not built into Windows or available through Windows Update yet.
So it seems on Intel platforms, the BE2000 is a drop-in replacement. AMD, for some reason, not so much.
Followed up with ASRock asking if AMD support was something that may come in the future and they said: