When will the patches be stable enough that one would -with a reasonable degree of certainty- no longer expect save corruption anymore in the process? Because I will not, can not, do the first couple hours yet again at this point. I may roll another character when things have settled down and any further twiddling will be mostly cosmetic, but right now, no. BG3 is on hold for me now.
Try turning off cloud saves for specifically BG3. Each time you quick save the file is about 10 to 20 MB, so default game settings give you 25 quick saves and 25 auto saves, plus any manual saves you did. If you play long enough in a single session you could be having 1GB of save files steam tries uploading after you close the game. If you have slow upload it could take awhile and I’ve seen people close steam too quickly or crash and it screws up the in progress uploads. Turning off cloud saves will stop that. Just backup your saves elsewhere just in case.