Most people taking popular drugs like Ozempic and Wegovy to lose weight have shed significant pounds.

Summary

As many as 1 in 5 patients may not lose significant weight with GLP-1 drugs like Wegovy and Ozempic, despite their popularity and effectiveness in clinical trials.

Experts attribute this variability to genetic, hormonal, and brain-based differences in regulating energy, as well as factors like sleep apnea or medications that hinder weight loss.

Non-responders often face frustration, but doctors stress alternative options, including different medications, lifestyle adjustments, or older treatments.

  • marine_mustangEnglish
    151·
    10 hours ago

    “As many as” 20% so, less than 20%? So it’s more than 80% effective?

    • reallykindasorta@slrpnk.netEnglish
      10·
      9 hours ago

      The article is about that 20% and how they’re feeling pretty shitty after taking a drug that works for 80% and not seeing weightloss despite the significant hype. It’s basically obesity experts trying to calm expectations slightly—the drug works for a lot of people but you can’t count on it being a magic bullet for everyone.