Actual article. https://www.cell.com/cell/fulltext/S0092-8674(25)00210-7

Essentially they find that interleukin-6 (IL-6) a well-known inflammatory signal is important to neuronal lymphatics which are key to brain waste removal. Frankly, not too surprising imo but they do drill it down very well to what cells are effectors/affected. They use a drug, PLX5622, to inhibit this IL-6 activity and see significant improvement to mice where neuronal inflammation had been induced, genetically or surgically.

I’m very sleepy so didn’t read into any side-effects they notice or discuss as possibilities.

I wish my brain could take a shit but it don’t sleep no good

Brain needs a good wash

So pooping improves your memory? 😁

Brain pooping (waste removal via cerebrospinal fluid).

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