This article discusses the effects of vitamin D supplementation on major cardiac events, based on a large randomized controlled trial, the D-Health Trial.
The trial involved 21,315 older Australians and aimed to assess the impact of monthly vitamin D supplementation (60,000 IU) on the incidence of major cardiovascular events. The study found no significant difference in the rate of major cardiovascular events between those receiving vitamin D and those receiving a placebo.
However, a few individual events showed statistically significant differences, albeit very slight. Despite these minor positive results, the trial overall adds to existing research suggesting that vitamin D supplementation offers no significant cardiovascular benefits.
What about depression and other believed benefits like a functioning immune system
You find articles citing studies on sciencebasedmedicine.org
Tl;dr:
- A study published in The BMJ suggests vitamin D might prevent autoimmune disease, but there are reasons to be cautious
- A randomized controlled trial finds vitamin D supplementation has no effect on depression. This adds to the long list of medical conditions for which vitamin D supplementation has turned out to be ineffective.
