The effects of vitamin D supplementation on major cardiac events | Science-Based Medicine
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A large randomized controlled trial of vitamin D supplementation generates good data to show there is likely no benefit.

This article discusses the effects of vitamin D supplementation on major cardiac events, based on a large randomized controlled trial, the D-Health Trial.

The trial involved 21,315 older Australians and aimed to assess the impact of monthly vitamin D supplementation (60,000 IU) on the incidence of major cardiovascular events. The study found no significant difference in the rate of major cardiovascular events between those receiving vitamin D and those receiving a placebo.

However, a few individual events showed statistically significant differences, albeit very slight. Despite these minor positive results, the trial overall adds to existing research suggesting that vitamin D supplementation offers no significant cardiovascular benefits.

  • lewosadebuOPM
    2·
    1 year ago

    You find articles citing studies on sciencebasedmedicine.org

    Tl;dr:

    • A study published in The BMJ suggests vitamin D might prevent autoimmune disease, but there are reasons to be cautious
    • A randomized controlled trial finds vitamin D supplementation has no effect on depression. This adds to the long list of medical conditions for which vitamin D supplementation has turned out to be ineffective.