My wife puts the nearest hot sauce on everything. Don’t get me wrong, I appreciate spice, but she has no regard for the flavor profile of the sauce or the food. Maybe your wife’s the same. I’ve been slowly trying to get her to pair her spice sources thoughtfully.

Tabasco is a sup-par hot sauce for most pizzas. Red pepper flakes are best in my opinion, and pack plenty of heat and flavor. I had some serrano basil sauces that went great with pizza, which I think could be expected with any sauce featuring basil. If you’re feeling fancy, Truff goes great on pizza too. If you’re going to do Tabasco, at least do the smokey chipotle.

Different sauces taste different, and pair differently with different foods. Some flavors synergize with a dish, some overpower it, and some clash. I wouldn’t say regular Tabasco necessarily clashes with pizza, but I think it usually overpowers the other notes. There are more delicious choices.