Twice-yearly shots used to treat AIDS were 100% effective in preventing new infections in women, according to study results published Wednesday.

There were no infections in the young women and girls that got the shots in a study of about 5,000 in South Africa and Uganda, researchers reported. In a group given daily prevention pills, roughly 2% ended up catching HIV from infected sex partners.

“To see this level of protection is stunning,” said Salim Abdool Karim of the injections. He is director of an AIDS research center in Durban, South Africa, who was not part of the research.

The results in women were published Wednesday in the New England Journal of Medicine and discussed at an AIDS conference in Munich. Gilead paid for the study and some of the researchers are company employees. Because of the surprisingly encouraging results, the study was stopped early and all participants were offered the shots, also known as lenacapavir.

      • @[email protected]
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        442 months ago

        Yeah, I’m getting jaded as I get older. The optimist in me recognizes how ground breaking this is, and thinks there’s a real possibility of actually eradicating AIDS. The pessimist in me remembers covid.

        • @funkless_eck
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          82 months ago

          if PrEP had been invented 25 years ago it would be banned

          we’ve come a long way

    • @[email protected]
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      -42 months ago

      If there’s profit to be made treating HIV/AIDS symptoms without curing, the profit motive health industry won’t like this. Solve the problem, their profits go away.

        • @[email protected]
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          52 months ago

          We can speculate very easily.

          There’s a trade-off, cost-benefit analysys. If a disease is so catastrophic that it kills everyone fast, well you’re not gonna make profit off them ever, because they die. Cure this one.

          What about diseases that can be controlled somewhat, and only affect small amounts of the population? What if for them to stay alive they have to stay on a regular concoction of expensive pharmaceuticals either forever or for a long time? And they can still go to work? Why cure this, out of altruism? That’s not how capitalism works.

          Let’s just say, for shits and giggles, we could cure immediately the common cold and mild influenza, forever. No more cough and cold over the counter medicine needed, much less pain and fever reducers. Local pharmacies don’t need to stock this stuff anymore. The companies that produce and sell these are all tied to wallstreet. Getting colds doesn’t stop you from working (or buying/consuming). Shit, I work with “men” who are “tough” who never call out of work sick because “I’m not a pussy” (cultural hardwork ethic propaganda nonsense).

          Etc., etc. You get my point.

          • @thetreesaysbark
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            2 months ago

            I’m not sure why you’re being downvoted.

            Correct me if I’m wrong but you’re not saying this is a good thing. Just that it is a thing.

            Makes sense to me. But I concede that I’m ignorant of what diseases we have cured recently, and too tired to research it right now.

            • @[email protected]
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              82 months ago

              Yellow fever, cholera, mumps, polio, measles, and malaria were endemic in the US prior to their eradication. By “endemic” I mean children got them as often as chicken pox. They were almost unavoidable and killed millions.

              Measles and mumps are making a comeback due to anti-vax losers, but the others are still gone.

            • @[email protected]
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              62 months ago

              The downvotes are meh, I’ve made similar comments that got more upvoted. Lemmy is a fickle beast and probably depends on the crowd at the time and their mood or the article or whatever.

              You’re correct, I was not saying this is good by any means. I want the profit motive removed from everything healthcare related. I was just giving an exaggerated simple example of how the capitalist profit motive could (and arguably does) work in some instances.

      • @[email protected]
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        102 months ago

        Then some other company will do it. Not all world is US and A. Is some areas like Europe the states would be more than happy to order those vaccines to treat their citizens. There’s demand made by public health organizations, there will be someone willing to join the race and eat that cake.

  • Flying SquidM
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    322 months ago

    Please make this affordable in the U.S.

    I have a feeling it won’t be.

    • Diplomjodler
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      272 months ago

      But then people might have sex without fear! That’s bound to make baby Jesus cry!

        • Diplomjodler
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          42 months ago

          AIDS has been the most dangerous STD for decades. It has changed attitudes to sex worldwide. Having a vaccine is going to change them again.

          • @[email protected]
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            12 months ago

            There’s already very effective medicine available in the west to treat and prevent HIV/AIDS, we call it PrEP.

            • @[email protected]
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              52 months ago

              This is more effective than prep and easier, because you only need a shot every 6 months. The testing for this new shit involved using prep for the control group.

              The new medicine worked so well they stopped the trial and gave the control group the shot. No one with the shot got sick at all. If they had continued with the control group, a few of them would have gotten AIDS.

            • Diplomjodler
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              12 months ago

              Most other STDs are curable with antibiotics. And there’s contraceptives. AIDS was always something different, even after it was treatable.

        • @[email protected]
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          12 months ago

          Not to sell out my community but I know quite a few people whose condom use went down after they got on PrEP

  • ShadowRam
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    -22 months ago

    twice-yearly

    I wonder why they went with that, instead of saying bi-annually

    • @deranger
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      2 months ago

      Is biannual twice yearly or every two years?

      If you look it up, it’s both. IMO all these words are useless. Biweekly, bimonthly, etc.

      • Clay_pidgin
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        62 months ago

        Instead of biweekly I specify fortnightly. Is there a bimonthly equivalent? Fortweekly?

        • @[email protected]
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          72 months ago

          We should make it a thing. Let’s regroup in a fortweek and see how we’re getting on.

        • @Kanzar
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          32 months ago

          If you use the word fortnight, it’s likely you aren’t from North America.

          • Clay_pidgin
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            22 months ago

            I am American, but I won’t use biweekly because it is ambiguous.

      • BarqsHasBite
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        32 months ago

        I think it’s trended to mean every 2. The original commentator wants chaos.

    • @[email protected]
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      102 months ago

      It is clearer. What I learned at work is to write documents in high school language so that everyone can understand them.

      • @[email protected]
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        22 months ago

        For research studies you are unironically required to write consent forms so a middle schooler can understand them because that’s the average level of comprehension in the USA

    • Flying SquidM
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      72 months ago

      They could have gone with “every six months” too. I think any of them work, although as other say biannually can mean every two years as well, leading to confusion.

  • Ogmios
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    2 months ago

    10 years later: You may be entitled to compensation…