Ooo interesting. The parallels with CFS are fascinating.
I wasn’t even aware of that. chronic fatigue syndrome was actually real.
I thought I was just like side- depression.
is there anything known about CFS?
what causes it or how long it lasts or anything?
I know nothing about it except for like a comedy sketch from the 2000s at some point.
Lifelong disease usually triggered by viral infections. Very functionally disabling.
Known immune abnormalities which seem to affect the brain and mitochondria. I think @[email protected] is specialised in it.
Also “chronic fatigue syndrome” was the name back when it was classified as psychological. Now that it’s classified as neuroimmune the name has been changed to Myalgic Encephalomyelitsis (ME) (Or ME/CFS).
As usual though for a medium quality source like ScienceAlert, the article is written by someone who has no specialisation in Long COVID/ME, or even medicine. So there’s a bit of oversimplification and overstating findings from one study in that article. Very few researchers think it’s a brain injury. Most think the immune system has been compromised (with some deficiencies and abnormalities) and it’s affecting the brain in unknown ways (hence the abnormalities found. It’s weird though because the immune system problems seem to cause some immunodeficiencies but also autoimmune reactions. They’ll need to be quite a bit more studies before we get a clear picture.
Couldn’t have said it better. And yes, science journalism often is basically repeating and dumbing down what a study says, but in science, and especially in medicine, a lot of studies tend to be wrong, make false assumptions, or overstate their findings, while journalists tend to take them for their word. There’s a reason you hear of a new cancer treatment in the news every other week but few actually make it past FDA approval.
wow, thank you so much for the detailed answer, I’m fascinated chronic fatigue syndrome turned out to be a neuroimmune disorder.
is ME genetic or do you just get unlucky as far as we know so far?
We don’t really know. But theres a giant GWAS (Genome Wide Association Study) called Decode ME with I think upwards of 25’000 pariticpants which is coming out in the next year. So we’ll know a whole lot more then. Hopefully it might lead to treatments.
thanks, I totally slept on those developments.
that is very exciting
Using high-resolution scanners, researchers at the Universities of Cambridge and Oxford have shown microscopic, structural abnormalities in the brainstems of those recovering from COVID-19.
Signs of brain inflammation were present up to 18 months after first contracting the SARS-CoV-2 virus.
[…]
In living brains of those with long COVID, however, conventional MRI studies have shown no structural abnormalities in the brainstem.
Do these people not proof-read their own articles?
Normal hospital-type MRI scanners can’t see inside the brain with the kind of chemical and physical detail we need. But with 7T (7 Tesla) scanners, we can now measure these details
Not the best article, but I think what they are trying to say over multiple paragraphs is that new higher resolution MRI machines can see the damage that normal lower resolution MRI can’t see
what type of abnormalities are they seeing specifically?
FTA: Signs of ongoing inflammation in the brainstem, something that is seen in people with traumatic brain injury and people with chronic fatigue syndrome.
oh, interesting.
so this new study is saying they can see on a small enough scale to find that scientifically consistent and significant inflammation in the brainstem directly linked to covid?
Removed by mod
deleted by creator
The abnormalities are only visible with a 7T scanner, and not conventional MRIs.